@article { author = {}, title = {Synthesis and Pharmacological Evaluation of Some Novel Isatin Derivatives for Antimicrobial Activity}, journal = {Journal of Sciences, Islamic Republic of Iran}, volume = {19}, number = {3}, pages = {-}, year = {2008}, publisher = {University of Tehran}, issn = {1016-1104}, eissn = {2345-6914}, doi = {}, abstract = {In the present work, a series of new 5-substituted-3-(4-arylimino)-1-[5-mercapto(1,3,4-oxadiazolyl)]-methyl-indol-2-one (4a-g) have been synthesized by heterocyclization of 5-substituted-3-(4-arylimino)-2-oxo-1-indole acetylhyrazide (3a-g) on treatment with CS2 in ethanolic KOH. The compound 4a was characterized by its elemental analysis, IR, 1HNMR and Mass Spectroscopy. The synthesized compounds (4a-g) were evaluated for in vitro antibacterial activity and antifungal activity against various strains of bacteria and fungi.}, keywords = {}, url = {https://jsciences.ut.ac.ir/article_31895.html}, eprint = {https://jsciences.ut.ac.ir/article_31895_981b4487122b372fdfd27ff42d00fa12.pdf} }