%0 Journal Article %T Synthesis of some New Thiosemicarbazide and 1,3,4-Thiadiazole Heterocycles Bearing Benzo[b]Thiophene Nucleus as a Potent Antitubercular and Antimicrobial Agents %J Journal of Sciences, Islamic Republic of Iran %I University of Tehran %Z 1016-1104 %D 2005 %\ 03/01/2005 %V 16 %N 1 %P - %! Synthesis of some New Thiosemicarbazide and 1,3,4-Thiadiazole Heterocycles Bearing Benzo[b]Thiophene Nucleus as a Potent Antitubercular and Antimicrobial Agents %R %X Reaction of 2-hydrazinocarbonyl-3-chloro-5-phenoxy-benzo[b] thiophene with different substituted phenyl isothiocyanate gave N-substituted arylthiosemi-carbazide derivatives (1a-h). 1,3,4-Thiadiazole derivatives (2a-h) were prepared by the cyclization of arylthiosemicarbazides (1a-h) with concentrated sulphuric acid. All the compounds were screened for their antitubercular activity against Mycobacterium tuberculosis (H37Rv) and antimicrobial activity against various microorganisms %U https://jsciences.ut.ac.ir/article_31624_0196f34b7e1c5995b59bc6f9d406a688.pdf