%0 Journal Article %T STRUCTURAL EVALUATION OF THE ENZYMATIC RESOLUTION OF TRICYCLO[5.2.1.02,6]DECENE-2-CARBOXYLATES USING PIG’S LIVER ESTERASE %J Journal of Sciences, Islamic Republic of Iran %I University of Tehran %Z 1016-1104 %D 2000 %\ 09/01/2000 %V 11 %N 3 %P - %! STRUCTURAL EVALUATION OF THE ENZYMATIC RESOLUTION OF TRICYCLO[5.2.1.02,6]DECENE-2-CARBOXYLATES USING PIG’S LIVER ESTERASE %R %X Moderate to excellent entantio- and stereoselectivities (ee’s 54-100%) were observed in PLE catalyzed hydrolysis of (±)-ethyl 5-oxo-endo-tricyclo[5.2.1.02,6] deca-8-ene-2-carboxylate 5 and the structurally related open chain bicyclic structures (±)-ethyl 3-acetylbicyclo[2.2.1]hept-5-ene-2-carboxylates 7, 9 and (±)-ethyl 3-propanoylbicyclo[2.2.1]hept-5-ene-2-carboxylates 8, 10. A pronounced preference for hydrolysis of the exo- vs. the endo-ester function was observed. %U https://jsciences.ut.ac.ir/article_31839_1cc474b64bcd5ab8b4f82e98ca1565fe.pdf