ORIGINAL_ARTICLE
EDITORAL
https://jsciences.ut.ac.ir/article_31317_ead83919dc08105eb122c8242471c4f4.pdf
1990-06-01
ORIGINAL_ARTICLE
EFFECT OF TOXOCARA CANIS SECOND STAGE
LARVAE ON THE HOST IMMUNE SYSTEM
We have studied functional alteration of immunocytes in mice following
inoculation of Toxocara canis second stage larvae. Results indicated depression
of lymphocyte blastogenesis in response to concanavalin-A,
phytohemagglutinin and allogeneic non B-cells; however, B-cell polyclonal
activation was not affected as indicated by the production of total IgG.
In contrast, frequency of antibody secreting cells was reduced. Similarly,
interleukin-1 and interleukin-2 production were not affected by Toxocara
canis infection. Furthermore, spleen cells of infected mice synthesized
more prostaglandin E than uninfected animals. This data suggests that
Toxocara canis infection induces suppression of both cell mediated and
humoral immunity; perhaps due to an increase of prostoglandin E2 production.
https://jsciences.ut.ac.ir/article_31318_cb4fdba99aa849a234a5a54676a1ceb9.pdf
1990-06-01
ORIGINAL_ARTICLE
CHARACTERIZATION OF HIGH MOBILITY
GROUP NONHISTONE PROTEINS FROM
DIFFERENTIATED NEUROPHILIC
GRANULOCYTES
The quantitative changes of the high mobility group (HMG) nonhistone
chromosomal proteins in nondividing, differentiated peritoneal exudate
neutrophils were identified by their solubility, electrophoretic mobility on
both SDS and acetic acid gels, densitometric traces and elution profile on
CM-sephadex. The results indicated that in neutrophils, HMGl undergoes
a considerable reduction (80%) compared to thymus proteins, However,
HMG2 and HMG17 remain constant. Also, HMG14 was not detectable
in neutrophils implying the possible role of the HMG proteins in genome
function
https://jsciences.ut.ac.ir/article_31319_732ab081fb620f100d3a6e94f66ef9b4.pdf
1990-06-01
ORIGINAL_ARTICLE
IMMOBILIZATION OF MICROBIAL CELLS FOR
THE PRODUCTION OF ORGANIC ACIDS
Techniques of immobilization of microbial- cells have been established
by multifunctional reagents such as glutaraldehyed on a solid support.
Immobilized cell reactor was designed to demonstrate stability of cross
linking of whole cells for the production of organic acids. An eighty-six
percent conversion of glucose was obtained for an eight hour retention
time. The immobilized cell reactor is about 5-8 times faster than the
continuous stirred tank reactor with free microbial cells. An appropriate
kinetic model was obtained using immobilized propionibacterium acidipropionici
on solid support
https://jsciences.ut.ac.ir/article_31320_d92077deed93cf26b64a4e386d4fba81.pdf
1990-06-01
ORIGINAL_ARTICLE
A STUDY OF THE SILYLATION REACTION OF
CYANOEPOXIDES WITH TRIMETHYLCHLOROSILANE
IN THE PRESENCE OF MAGNESIUM
In the presence of magnesium and hexamethylphosphorictriamide,
HMPT, trimethylchlorosilane, TMS-C1, reacts with cyanoepoxides to give
related compounds. Ring cleavage at ? - position of cyanoepoxide, 1,
followed by the addition of two trimethylsilyl groups leads to 2 then
substitution of OSiMei by trimethylsilyl or H takes place to give ?, ? -
bis (trimethylsilyl) nitrile or ? - trimethylsilylnitrile, respectively. Silylation
reaction of cyanoepoxide 4 gives compounds 5 and 6, but silylation
of 9 gives only ? - monosilylated derivative 10. Silylation of a, ?-
diphenylcyanoepoxide, 11, leads to polysilylated products, by participation
of both nitrile and epoxide functions
https://jsciences.ut.ac.ir/article_31321_c01cf05c3714c065c0f15e3a647a2792.pdf
1990-06-01
ORIGINAL_ARTICLE
REACTIVITY OF N-SUBSTITUTED p-BENZO AND p-NAPHTHOQUINONEIMINE N-OXIDES TOWARD DIPOLAROPHILES
The dipolar cycloaddition reactivity of N-(1-naphthy1)-1,4- benzoquinoneimine
N-oxide and N-phenyl-1,4- naphthoquinoneimine Noxide
are investigated, The latter gives the expected adducts with common
dipolarophiles such as acrylonitryle, methyl methacrylate, dimethylacetylene
dicarboxylate and N-phenylmaleimide. The reactivity of
the former nitrone is found to be minimal. It undergoes, however, an
anomalous reaction with DMAD to give, after rearrangement, 1-(4-hydroxypheny1) 3, 3-dicarboxymethylbenzooxindole
https://jsciences.ut.ac.ir/article_31322_9cbeef85e20624189348b016b9609208.pdf
1990-06-01
ORIGINAL_ARTICLE
SYNTHESIS OF PURINE
ACYCLONUCLEOSIDES HAVING PRONOUNCED
ANTIVIRAL ACTIVITY
The synthesis of a series of purine analogues of the acyclonucleoside
compound 14 (acyclovir) is described. Compounds in this series have been
shown to have pronounced activity against herpes virus-type l(HSV-1).
The anti-viral activities of other analogs whose syntheses were recently
reported [1] by us are also described
https://jsciences.ut.ac.ir/article_31323_472f01058c22075e4b364fd5c5d30f7a.pdf
1990-06-01
ORIGINAL_ARTICLE
THE ROLE OF CHLOROMETHYL ETHERS IN
THE FORMATION OF N(7) - AND N(9)-ALKYLATED
ISOMERS OF ADENINE
SYNTHESIS OF 2-[9-(ETHOXYMETHYL)
ADENYL] PHOSPHONATE
The structural features of chloromethyl ethers are shown to have a significant effect on the formation of N(7)- or N(9)- alkylated isomers of purine acyclo-nucleosides. The chemical synthesis of 2-[9-(ethoxymethyl) adenyl] phosphonate is described. This compound is active against herpesviruses.
https://jsciences.ut.ac.ir/article_31324_b30cb1658eaad9876426712d7f51b27c.pdf
1990-06-01
ORIGINAL_ARTICLE
NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES
Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles
(2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole
(15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3-
pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and antifungal activities of compounds 5, 6, and 7 against a number of microorganisms were determined
https://jsciences.ut.ac.ir/article_31325_61cf2735d9cfb28c7d99ac4350f15b56.pdf
1990-06-01
ORIGINAL_ARTICLE
ON MODALITY AND DIVISIBILITY OF POISSON
AND BINOMIAL MIXTURES
Some structural aspects of mixtures, in general, have been previously
investigated by the author in [I] and [2]. The aim of this article is to
investigate some important structural properties of the special cases of
Poisson and binomial mixtures in detail. Some necessary and sufficient
conditions are arrived at for different modality and divisibility properties
of a Poisson mixture based on similar properties of its mixing distribution.
These simplify and improve the results of Holgate [7], Shanbhagh &
Westcott [12] and Forst [6] in this connection. Whenever the preservation
of a property of the mixing distribution is not held by the mixture, proper
counterexamples are provided to illustrate the point. Then, a similar argument
is employed to extend these ideas analogously to the case of binomial
mixtures.
https://jsciences.ut.ac.ir/article_31326_f8cedb34a718da263d0b5a03a83aa202.pdf
1990-06-01
ORIGINAL_ARTICLE
ON FUZZY IDEALS OF A RING
The concepts of L-fuzzy ideal generated by a L-fuzzy subset, L-fuzzy
prime and completely prime ideal where L is a complete lattice are considered
and some results are proved
https://jsciences.ut.ac.ir/article_31327_378e6bb13f5ed877d91b14a4cbb2b0ba.pdf
1990-06-01
ORIGINAL_ARTICLE
AN INTRODUCTION TO THE THEORY OF DIFFERENTIABLE
STRUCTURES ON INFINITE INTEGRAL
DOMAINS
A special class of differentiable functions on an infinite integral domain
which is not a field is introduced. Some facts about these functions are
established and the special case of z is studied in more detail
https://jsciences.ut.ac.ir/article_31328_02b22f44bd766577ce2fc43976c778cf.pdf
1990-06-01
ORIGINAL_ARTICLE
DEVELOPMENT IN STRING THEORY
The string theory is a fast moving subject, both physics wise and in the
respect of mathematics. In order to keep up with the discipline it is important
to move with new ideas which are being stressed. Here I wish to give
extracts from new papers of ideas which I have recently found interesting.
There are six papers which are involved:
I ."Strings formulated directly in 4 dimensions " A. N. Schellekens
II. "Remarks on 40 strings" C.Bachas
III. "Informal introduction to extended algebras and conformal field
theories with c 1 " F.Ravanini
IV. "Skein relations and braiding in topological gauge theory" and
"Modular geometry and the classification of rational conformal field
theories " S. Mukhi
V. "Chern-Simons theories" E. Witten
VI. "Duality and the rdl of nonperturbative effects on the world-sheet"
J.Lauer, J.Mas and H.P. Nilles
https://jsciences.ut.ac.ir/article_31329_062117b22f8e7f0c121b25936d4d7e8f.pdf
1990-06-01
ORIGINAL_ARTICLE
HIGH RESOLUTION LASER SPECTROSCOPY IN
COLD SUPERSONIC MOLECULAR BEAMS
COOLING, REDUCTION OF DOPPLER WIDTH
AND APPLICATION
The cooling of molecules during the adiabatic expansion of supersonic
seeded molecular beams is reviewed and illustrated by the example of
NO -molecules. The reduction of the Doppler width by collimation of the
beam and the cooling to low rotational temperatures brings a significant
simplification of the complex NO -absorption spectrum and allows its
assignment. The measured rotational temperature is T = 10°K. Some
examples from our work illustrate this promising technique of high resolution
laser spectroscopy in cold beams
https://jsciences.ut.ac.ir/article_31330_2c76a4fc7cc0ec4bb29e83473d835e23.pdf
1990-06-01