ORIGINAL_ARTICLE
THERMODYNAMIC STUDIES OF THE INTERACTION
OF SODIUM N-DODECYL, SULPHATE
WITH CALF - THYMUS WISTONE H3
The binding of Sodium n-dodecyl sulphate (SDS) to histone H3 was studied in the
pH range 3.2-10 by equilibrium dialysis at 27? and 3 7 ?c .T he binding data have been
used to obtain the Gibbs free energy of interaction using a theoretical model of the
Wyman binding potential; and the enthalpy of interaction from the temperature
dependence of theequilibriumconstantsfronr theVan't Hoff re1ation.The enthalpy of
interaction of H3 and SDS is exothermic in some buffer solutions which is in marked
contrast to other histone - SDS complexes, The entropy of initial interaction of H3 and
SDS is negative in some other buffer solutions with increasing binding of SDS, the
entropy becomes positive.
https://jsciences.ut.ac.ir/article_31450_be11f1d63b9b27244baa9453d00aa32f.pdf
1990-08-01
ORIGINAL_ARTICLE
THE INFLUENCE OF CHARGE DENSITY ON
THE INTERACTION BETWEEN SODIUM NDUDECYL SULPHATE (SDS) WITH H1
The binding data for the interaction of SDS with HI, in aqueous solution at various
ionic strengths have been measured by equlibrium dialysis, and investigated
spectroscapicaliy. The effect of charge density on the interaction is shown to be of
considerable interest. The presence of NaCl causes conformational changes on the
structure of HI; whereas this phenomena seems to become more intensified upon
contact with SDS. The existence and the importance of charge density which cause
additional forces in the macromolecular structures at identical ionic strengths is
reported
https://jsciences.ut.ac.ir/article_31451_739f6910021e541107d13f344a3d58e6.pdf
1990-08-01
ORIGINAL_ARTICLE
A QUANTUM CHEMICAL STUDY OF STRUCTURE
-ACTIVITY RELATIONSHIPS OF DIHYDROPYRIDINE
CALCIUM ANTAGONISTS
Quantum chemical (MNDo)caleulations have beenused toelucidate the molecular
properties and structure - activity relationships of dihydropyridine (DHP) type
calcium antagonists. There is a good corielation between the net atomic charges on
various atoms of the 4 - phenyl ring of dihydropyridines and pharmacological activity.
.Also, activity decreases with increasing free rotation of the phenyl ring. These results
indicate that the binding of the 4 - phenyl ring to a rigid part of the receptor plays an
important part in the activity of DHP calcium antagonists
https://jsciences.ut.ac.ir/article_31452_58935346704b8722d1ff7c4ee06268da.pdf
1990-08-01
ORIGINAL_ARTICLE
SPECTROPHOTOMETRIC DETERMI NATION
OF OSMIUM (VIII) WITH 1-HYDROXY 2-
PYRIDINE - THIONE (SODIUM SALT) AS A
REAGENT
A spectrophotometric study of osmium (VIII) complex of 1-hydroxy 2- pyridine
thione (HPT) is presented. A red-violet complex, 0 s (HPT) is formed in a highly
acidic solution, and shows maximum absorbance at 500 nm with molar absorptivity
of 5.12 x 101. mol . cm . Beer's law is obeyed in the range of 3-60 ppm. Sandel's
sensitivity of the method is 0.37 ?g.cm per0.001 ab sorbance unit. V (V), Pt (IV),
Cu (II), Sn (IV), Cr (VI), and NO . interference. To overcome the interference and
improve the selectivity, the 0 s (VIII) as OsO isextracted inCC1 and theextracted
0s (VIII) is converted to the complex and measured spectrophotometrically. This
method reduces the number of interferences to V(V), Pt (IV), and NO -. The
method offers the advantages of simplicity, speed and high precision. A spot test for
the detection of traces of osmium is also presented
https://jsciences.ut.ac.ir/article_31453_00551683e92324de5cad0465a3e6028d.pdf
1990-08-01
ORIGINAL_ARTICLE
SYNTHESIS AND SPECTROSCOPIC STUDIES
OF THIOCYANATO -DERIVATIVES OF
CU-Mo-S CLUSTERS
The complexes [MoS (CUNCS) ] w hen x = 2,3,4 and [MoOS , (CUNCS) ] when
y = 2, 3 have been prepared by the reaction of CuSCN with [P(C H ) ] [MoS ] or
[P(C H ) ] [MOOS ] in dry degassed acetone or DMFsolution and recrystallized from
dichloromethane, the attempted preparation of [MoS (AgSCN) ] and [MOOS
(AgSCN) ] failed. The Raman, IR, UV/VIS, C-nmr and Mo-nmr spectra of the
complexes are discussed
https://jsciences.ut.ac.ir/article_31454_07ff653a63e2b625b80982a96d04dc47.pdf
1990-08-01
ORIGINAL_ARTICLE
REACTION OF TRIMETHYLCHLOROSILANE
WITH EPOXYKETONES IN THE PRESENCE OF
MAGNESIUM
Mixture of the trimethylchlorosilane, magnesium and hexamethylphosphorictriamid,
HMPT, react with epoxyketones to produce tetrasiliciated compounds, which
are the results of the addition of two trimethylsilyl (TMS) groups to the carbonyl
function and two TMS groups to the expoxide cycle. After elimination of (Me Si) O
siliciated enoxysilanes are obtained which under acidic conditions gives B - siliciated
ketones
https://jsciences.ut.ac.ir/article_31455_e2c225166a78d20d2203ac106b0c2ffc.pdf
1990-08-01
ORIGINAL_ARTICLE
THE SYNTHESES OF 1- [[2- AMINO -1 -
(HYDROXYMETHYL) ETHOXY] METHYL]
URACIL AND 1, 3-BIS (2- HALOETHOXYMETHYL)
PYRIMIDINE
The syntheses of the title compounds are described. 1- [[2- Amino -1 -
(hydroxymethyl) ethoxy] methyl] uracil exhibitslittleactivity against herpesviruses
(HSV) in vivo
https://jsciences.ut.ac.ir/article_31456_46dc10c97718366853c6dccda6c6c3d3.pdf
1990-08-01
ORIGINAL_ARTICLE
DEUTERIUM STUDIES IN THE DISPROPORTIONATION
OF THIOXANTHYLIUM SALTS
Deuterium labelling is used to show that the disproportionation of thioxanthylium
salts involve transfer of a hydride, (deuteride) ion from the9-positionof one molecule
of the compound, as its hydro], to the 9 - position of another molecule in the cation
form
https://jsciences.ut.ac.ir/article_31457_613b397666c90210b937501592a5fd70.pdf
1990-08-01
ORIGINAL_ARTICLE
SELENIUM HETEROCYCLES XXXX [I]
SYNTHESES OF 4- (2-PYRAZINYL) - 1, 2, 3:
SELENADIAZOLE AND 4- (2-PYRAZILYL)' -
l,2,3- THIADIAZOLE
Reaction of thionyl chloride with 2-acetyl-1- benzenesulfonylpyrrole semicarbazone
(6 c) gave 4 - (1- benzenesulfonyl-2 - pyrrolyl) - 1, 2, 3 -thiadiazole (lc).
Selenium dioxide oxidation of 2-acetylpyrazine semicarbazone (10) in acetic acid
afforded 4- (2-pyrazinyl) - 1, 2, 3- selenadiazole (4). Reaction of thionyl chloride
with compound 10 gave 4- (2-pyrazinyl) - 1, 2, 3- thiadiazole (3). Base catalized
decomposition of 4 afforded the cis-fulvene 13. Similarly, reaction of 3 with a base
gave the corresponding cis-fulvene 11. Heating compounds 11 or 13 gave
respectively the corresponding trans isomers 12 or 14.
https://jsciences.ut.ac.ir/article_31458_c7d458f9f0f3847a0a9fa94b154fb689.pdf
1990-08-01
ORIGINAL_ARTICLE
DIFFERENT TYPES OF ROCKBALLS AND
THEIR GENESIS FROM THE KARAJ FORMATION
(MIDDLE EOCENE) IN CENTRAL
ALBORZ, OF NORTHERN IRAN
https://jsciences.ut.ac.ir/article_31459_aed0e498a0d925ec4411696f6f5cb2e2.pdf
1990-08-01
ORIGINAL_ARTICLE
A CHARACTERIZATION OF EXTREMELY
AMENABLE SEMIGROUPS
Let S be a discrete semigroup, m (S) the space of all bounded real functions on S with
the usualsupremum norm. Let Acm (S) be a uniformly closed left invariant subalgebra
of m (S) with 1 c A. We say that A is extremely left amenable if there isamultiplicative
left invariant meanon A. Let P = {h ?A: h =|g-1,g | forsome g ?A, s ?S}. It isshown that .
A is extremely left amenable if and only if there is a mean ? on A such that ?(PA) = 0.
https://jsciences.ut.ac.ir/article_31460_8adab8d1ba3a4f8a163ddf0624182fb4.pdf
1990-08-01
ORIGINAL_ARTICLE
BAYES ESTIMATION USING A LINEX LOSS
FUNCTION
This paper considers estimation of normal mean ? when the variance is unknown,
using the LINEX loss function. The unique Bayes estimate of ? is obtained when the
precision parameter has an Inverse Gaussian prior density
https://jsciences.ut.ac.ir/article_31461_2dcace405328e1940cd7aa5e0aada135.pdf
1990-08-01
ORIGINAL_ARTICLE
THE POMERON IN A MODIFIED
MU LTIPERIPHERAL MODEL
There have been many attempts [I-31 to produce correct pomeron by putting the nparticle
production amplitude expht, in the unitarity integral equation. It was found
that for reasonable values of h one could not get the right picture of the slope of the
pomeron as a function of energy S4 .W e show that theinterference termsin the unitary
equation does not improve the slope either. However, a modified multiperipheral
model predicts a correct pomerpn
https://jsciences.ut.ac.ir/article_31462_5200f93ea3196528a67e467842f20335.pdf
1990-08-01