TY - JOUR ID - 31220 TI - THE EFFECT OF SULFUR MUSTARD ON GLUCOSE PHOSPHORYLATING ENZYMES AND LIVER CELLS IN MALE RATS JO - Journal of Sciences, Islamic Republic of Iran JA - JSCIENCES LA - en SN - 1016-1104 Y1 - 1990 PY - 1990 VL - 1 IS - 5 SP - EP - DO - N2 - A significant decrease of hepatic high-Km glucose- phosphorylating enzyme glucokinase (ATP- D- glucose 6- phosphotransferase, EC 2.7. 1.2, GK) and low-Km hexokinases (EC 2.7. 1.1. HK) activities were noticed in liver treated with 2, 2'- dichlorodiethyl sulfide (sulfur mustard, HD) when injectedinteraperitoneally to male rats in 114 LD50. This decrease occurred 1.5 to 5.5 hours after the injection. Simultaneously, a significant decrease in concentration of soluble protein and glycogen was also noted after2 hours. In addition some morphological changes on liver cells were noticed UR - https://jsciences.ut.ac.ir/article_31220.html L1 - https://jsciences.ut.ac.ir/article_31220_537ffa71b53759763881c34e65a8e0da.pdf ER -