TY - JOUR ID - 31432 TI - SYNTHESIS OF NORBORNENE FURYL ESTERS AND THEIR ENZYMATIC KINETIC RESOLUTION BY PIG LIVER ESTRASE (PLE) JO - Journal of Sciences, Islamic Republic of Iran JA - JSCIENCES LA - en SN - 1016-1104 Y1 - 1999 PY - 1999 VL - 10 IS - 3 SP - EP - DO - N2 - The reaction of furylacrylic acid with cyclopentadiene in toluene gave the expected Diels-Alder endo-and exo-adductsin -1 : 1 ratio. The adducts were separated by iodolactonization method to provide 3-endo-(2'-furyl) bicyclo 12.2.11 hept-5-ene- 2-exo-carboxylic acid and 3-exo-(2'-fury1)bicyclo 12.2.11 hept-5-ene-2-endocarboxylic acid. Esterification of these acids by MeI / HMPA gave the expected methyl esters. Kinetic resolution of racemic endo- and exo-ester adducts by PLE(phosphate buffer, pH, 8) provided the related optically active isomers UR - https://jsciences.ut.ac.ir/article_31432.html L1 - https://jsciences.ut.ac.ir/article_31432_18f26ff37fcce3eceb53fca8faa24757.pdf ER -