University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 THE ROLE OF CHLOROMETHYL ETHERS IN THE FORMATION OF N(7) - AND N(9)-ALKYLATED ISOMERS OF ADENINE SYNTHESIS OF 2-[9-(ETHOXYMETHYL) ADENYL] PHOSPHONATE - 31324 EN Journal Article The structural features of chloromethyl ethers are shown to have a significant effect on the formation of N(7)- or N(9)- alkylated isomers of purine acyclo-nucleosides. The chemical synthesis of 2-[9-(ethoxymethyl) adenyl] phosphonate is described. This compound is active against herpesviruses. https://jsciences.ut.ac.ir/article_31324_5b347a27844fa303dd8c02b7da1c9206.pdf