University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 15 1 2004 03 01 Synthesis of Isoxazoles and Cyanopyridines Bearing Benzo(b)thiophene Nucleus as Potential Antitubercular and Antimicrobial Agents - 31582 EN Journal Article Isoxazole (2a-l) and cyanopyridine (3a-l) derivatives have been prepared by condensing chalcones (1a-l) with hydroxylamine hydrochloride and malononitrile respectively. While compounds 1a-l have been synthesized by the reaction of p-(3’-chloro-2’-benzo(b)thiophenoylamino)-acetophenone with different aldehydes. All the compounds were screened for their antitubercular and antimicrobial activities. The structures of newly synthesized compounds were established on the basis of elemental analyses, IR, 1H NMR and Mass spectral data https://jsciences.ut.ac.ir/article_31582_9d4e43921a44fdfe09818f19f75bc4e8.pdf