University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 EDITORAL - 31317 EN Journal Article https://jsciences.ut.ac.ir/article_31317_01cc9bcfcd567d83304a3843b7169ba1.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 EFFECT OF TOXOCARA CANIS SECOND STAGE LARVAE ON THE HOST IMMUNE SYSTEM - 31318 EN Journal Article We have studied functional alteration of immunocytes in mice following inoculation of Toxocara canis second stage larvae. Results indicated depression of lymphocyte blastogenesis in response to concanavalin-A, phytohemagglutinin and allogeneic non B-cells; however, B-cell polyclonal activation was not affected as indicated by the production of total IgG. In contrast, frequency of antibody secreting cells was reduced. Similarly, interleukin-1 and interleukin-2 production were not affected by Toxocara canis infection. Furthermore, spleen cells of infected mice synthesized more prostaglandin E than uninfected animals. This data suggests that Toxocara canis infection induces suppression of both cell mediated and humoral immunity; perhaps due to an increase of prostoglandin E2 production. https://jsciences.ut.ac.ir/article_31318_81bfe052679288bbb4558009aab788f9.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 CHARACTERIZATION OF HIGH MOBILITY GROUP NONHISTONE PROTEINS FROM DIFFERENTIATED NEUROPHILIC GRANULOCYTES - 31319 EN Journal Article The quantitative changes of the high mobility group (HMG) nonhistone chromosomal proteins in nondividing, differentiated peritoneal exudate neutrophils were identified by their solubility, electrophoretic mobility on both SDS and acetic acid gels, densitometric traces and elution profile on CM-sephadex. The results indicated that in neutrophils, HMGl undergoes a considerable reduction (80%) compared to thymus proteins, However, HMG2 and HMG17 remain constant. Also, HMG14 was not detectable in neutrophils implying the possible role of the HMG proteins in genome function https://jsciences.ut.ac.ir/article_31319_365aa6ebdc3dbf28e7b9ea1c1b4d2908.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 IMMOBILIZATION OF MICROBIAL CELLS FOR THE PRODUCTION OF ORGANIC ACIDS - 31320 EN Journal Article Techniques of immobilization of microbial- cells have been established by multifunctional reagents such as glutaraldehyed on a solid support. Immobilized cell reactor was designed to demonstrate stability of cross linking of whole cells for the production of organic acids. An eighty-six percent conversion of glucose was obtained for an eight hour retention time. The immobilized cell reactor is about 5-8 times faster than the continuous stirred tank reactor with free microbial cells. An appropriate kinetic model was obtained using immobilized propionibacterium acidipropionici on solid support https://jsciences.ut.ac.ir/article_31320_9981ae50de43432c6299c5a4c5d30050.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 A STUDY OF THE SILYLATION REACTION OF CYANOEPOXIDES WITH TRIMETHYLCHLOROSILANE IN THE PRESENCE OF MAGNESIUM - 31321 EN Journal Article In the presence of magnesium and hexamethylphosphorictriamide, HMPT, trimethylchlorosilane, TMS-C1, reacts with cyanoepoxides to give related compounds. Ring cleavage at ? - position of cyanoepoxide, 1, followed by the addition of two trimethylsilyl groups leads to 2 then substitution of OSiMei by trimethylsilyl or H takes place to give ?, ? - bis (trimethylsilyl) nitrile or ? - trimethylsilylnitrile, respectively. Silylation reaction of cyanoepoxide 4 gives compounds 5 and 6, but silylation of 9 gives only ? - monosilylated derivative 10. Silylation of a, ?- diphenylcyanoepoxide, 11, leads to polysilylated products, by participation of both nitrile and epoxide functions https://jsciences.ut.ac.ir/article_31321_3b782fa395459a50d498b04c3ed93093.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 REACTIVITY OF N-SUBSTITUTED p-BENZO AND p-NAPHTHOQUINONEIMINE N-OXIDES TOWARD DIPOLAROPHILES - 31322 EN Journal Article The dipolar cycloaddition reactivity of N-(1-naphthy1)-1,4- benzoquinoneimine N-oxide and N-phenyl-1,4- naphthoquinoneimine Noxide are investigated, The latter gives the expected adducts with common dipolarophiles such as acrylonitryle, methyl methacrylate, dimethylacetylene dicarboxylate and N-phenylmaleimide. The reactivity of the former nitrone is found to be minimal. It undergoes, however, an anomalous reaction with DMAD to give, after rearrangement, 1-(4-hydroxypheny1) 3, 3-dicarboxymethylbenzooxindole https://jsciences.ut.ac.ir/article_31322_8b317894aac9e99eae82d7add674a995.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 SYNTHESIS OF PURINE ACYCLONUCLEOSIDES HAVING PRONOUNCED ANTIVIRAL ACTIVITY - 31323 EN Journal Article The synthesis of a series of purine analogues of the acyclonucleoside compound 14 (acyclovir) is described. Compounds in this series have been shown to have pronounced activity against herpes virus-type l(HSV-1). The anti-viral activities of other analogs whose syntheses were recently reported [1] by us are also described https://jsciences.ut.ac.ir/article_31323_fc7acef4b85e5816052c710a655dbc47.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 THE ROLE OF CHLOROMETHYL ETHERS IN THE FORMATION OF N(7) - AND N(9)-ALKYLATED ISOMERS OF ADENINE SYNTHESIS OF 2-[9-(ETHOXYMETHYL) ADENYL] PHOSPHONATE - 31324 EN Journal Article The structural features of chloromethyl ethers are shown to have a significant effect on the formation of N(7)- or N(9)- alkylated isomers of purine acyclo-nucleosides. The chemical synthesis of 2-[9-(ethoxymethyl) adenyl] phosphonate is described. This compound is active against herpesviruses. https://jsciences.ut.ac.ir/article_31324_5b347a27844fa303dd8c02b7da1c9206.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES - 31325 EN Journal Article Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and antifungal activities of compounds 5, 6, and 7 against a number of microorganisms were determined https://jsciences.ut.ac.ir/article_31325_b8a8ace231fae55cbad834ad5b66e3d6.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 ON MODALITY AND DIVISIBILITY OF POISSON AND BINOMIAL MIXTURES - 31326 EN Journal Article Some structural aspects of mixtures, in general, have been previously investigated by the author in [I] and [2]. The aim of this article is to investigate some important structural properties of the special cases of Poisson and binomial mixtures in detail. Some necessary and sufficient conditions are arrived at for different modality and divisibility properties of a Poisson mixture based on similar properties of its mixing distribution. These simplify and improve the results of Holgate [7], Shanbhagh & Westcott [12] and Forst [6] in this connection. Whenever the preservation of a property of the mixing distribution is not held by the mixture, proper counterexamples are provided to illustrate the point. Then, a similar argument is employed to extend these ideas analogously to the case of binomial mixtures. https://jsciences.ut.ac.ir/article_31326_13019fc8997b04326425e0c525115724.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 ON FUZZY IDEALS OF A RING - 31327 EN Journal Article The concepts of L-fuzzy ideal generated by a L-fuzzy subset, L-fuzzy prime and completely prime ideal where L is a complete lattice are considered and some results are proved https://jsciences.ut.ac.ir/article_31327_4b0cb9685dd1da13cd7d85b3e4de824f.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 AN INTRODUCTION TO THE THEORY OF DIFFERENTIABLE STRUCTURES ON INFINITE INTEGRAL DOMAINS - 31328 EN Journal Article A special class of differentiable functions on an infinite integral domain which is not a field is introduced. Some facts about these functions are established and the special case of z is studied in more detail https://jsciences.ut.ac.ir/article_31328_e82be97d50fa31e032f4789c6685ef05.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 DEVELOPMENT IN STRING THEORY - 31329 EN Journal Article The string theory is a fast moving subject, both physics wise and in the respect of mathematics. In order to keep up with the discipline it is important to move with new ideas which are being stressed. Here I wish to give extracts from new papers of ideas which I have recently found interesting. There are six papers which are involved: I ."Strings formulated directly in 4 dimensions " A. N. Schellekens II. "Remarks on 40 strings" C.Bachas III. "Informal introduction to extended algebras and conformal field theories with c 1 " F.Ravanini IV. "Skein relations and braiding in topological gauge theory" and "Modular geometry and the classification of rational conformal field theories " S. Mukhi V. "Chern-Simons theories" E. Witten VI. "Duality and the rdl of nonperturbative effects on the world-sheet" J.Lauer, J.Mas and H.P. Nilles https://jsciences.ut.ac.ir/article_31329_c2cb1fc76f1bbf73ce680c2b78aa328f.pdf

University of Tehran Journal of Sciences, Islamic Republic of Iran 1016-1104 1 3 1990 06 01 HIGH RESOLUTION LASER SPECTROSCOPY IN COLD SUPERSONIC MOLECULAR BEAMS COOLING, REDUCTION OF DOPPLER WIDTH AND APPLICATION - 31330 EN Journal Article The cooling of molecules during the adiabatic expansion of supersonic seeded molecular beams is reviewed and illustrated by the example of NO -molecules. The reduction of the Doppler width by collimation of the beam and the cooling to low rotational temperatures brings a significant simplification of the complex NO -absorption spectrum and allows its assignment. The measured rotational temperature is T = 10°K. Some examples from our work illustrate this promising technique of high resolution laser spectroscopy in cold beams https://jsciences.ut.ac.ir/article_31330_1a95a20ee480d3c53bd76874aaf30773.pdf