The binding data for the interaction of SDS with HI, in aqueous solution at various
ionic strengths have been measured by equlibrium dialysis, and investigated
spectroscapicaliy. The effect of charge density on the interaction is shown to be of
considerable interest. The presence of NaCl causes conformational changes on the
structure of HI; whereas this phenomena seems to become more intensified upon
contact with SDS. The existence and the importance of charge density which cause
additional forces in the macromolecular structures at identical ionic strengths is