Rashin Andayesh; Maryam Abrishamkar; Hossein Hodaee
Abstract
Bio-absorbent palm fiber was applied for removal of cationic violet methyl dye from water solution. For this purpose, a solid phase extraction method combined with the artificial neural network (ANN) was used for preconcentration and determination of removal level of violet methyl dye. This method is ...
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Bio-absorbent palm fiber was applied for removal of cationic violet methyl dye from water solution. For this purpose, a solid phase extraction method combined with the artificial neural network (ANN) was used for preconcentration and determination of removal level of violet methyl dye. This method is influenced by factors such as pH, the contact time, the rotation speed, and the adsorbent dosage. In order to find a suitable model of parameters and calculate the desired output, two radial basis function (RBF) and multi-layer perceptron (MLP) non-recursive functions, which are among widely used artificial neural networks, were used for training the input data. The performance of this method is tested by common statistical parameters including RMSE, MAE, and CE. The results show that the artificial neural network algorithm has a good performance in simulating and predicting the removal of violet methyl dye.
chemistry
Hamid-Reza Adhami; Paria Sharafi
Abstract
Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore cholinesterase inhibitors can improve the Alzheimer's ...
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Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore cholinesterase inhibitors can improve the Alzheimer's symptoms. In recent decades, marine creatures have become interested for their huge medicinal effects and potential of pharmaceutical preparations. Marine classifications contain pharmacologically active compounds with capibilities for improvement of cognitive disorders. This article provides a comprehensive overview of cholinesterase inhibitors from marines in 4 categories contain seaweeds, marine sponges, coelenterates and other invertebrates over the 47 years from 1970 to 2017 which resulted into important bioactive extracts and isolated compounds which representing a diverse range of structural classes such as pyrrole derivatives, sesquiterpene acetates, tetrazacyclopentazulene, bromotyrosine derivatives, plastoquinones, farnesylacetones and poly-alkylpyridinium polymers (Poly-APS). For each structural group, the important compounds with cholinesterase inhibition activities were introduced. The result showed marins can be considered as important sources to discover new cholinesterase inhibitiors.
chemistry
Alireza Foroumadi; Pegah Nouraie; Shahram Moradi Dehaghi
Abstract
In this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid was reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic ...
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In this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid was reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic catalyst in this organic transformation. This work was also accompanied by density functional theory (DFT) studies to justify the formation of final products.
chemistry
masoumeh ghalbi-ahangary; Ali Taheri; Parviz Rashidi-Ranjbar; Zahra Taheri
Abstract
In this paper, a new lumped kinetic model for methanol to propylene process (MTP) over Cerium-Hierarchical SAPO-34 catalyst was developed based on data obtained from a micro catalytic reactor in the temperature range of 390–450°C and at atmospheric pressure, using appropriate reaction network. The ...
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In this paper, a new lumped kinetic model for methanol to propylene process (MTP) over Cerium-Hierarchical SAPO-34 catalyst was developed based on data obtained from a micro catalytic reactor in the temperature range of 390–450°C and at atmospheric pressure, using appropriate reaction network. The Ce-HSAPO-34 zeolite was synthesized by hydrothermal method in the presence of n-poropylamine as a mesoscale template and pore size modifier. The reaction rate equation has been introduced with consideration of reaction mechanism and the parameters were optimized on the experimental data by genetic algorithm. Comparing the experimental and predicted data showed that the predicted values from the presented model are well fitted to the experimental data.
Roya Malekzadeh; Mohammad Arjmand; Reza Haji Hosseini; Atusa Vaziri; Zahra Zamani
Abstract
Abstract Epithelial Ovarian cancer is the leading cause of cancer mortality among women all over the world. As chemotherapeutics has many side effects, researchers have focused on the potential use of medicinal plants as natural antitumor agents. Xanthium strumarium studied in this work as a herbal anticancer ...
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Abstract Epithelial Ovarian cancer is the leading cause of cancer mortality among women all over the world. As chemotherapeutics has many side effects, researchers have focused on the potential use of medicinal plants as natural antitumor agents. Xanthium strumarium studied in this work as a herbal anticancer agent. This study aimed to evaluate the antitumor effect and metabolic alterations caused by the root extract of X. strumarium on human ovarian cancer cell line (A2780cp), using NMR-based metabolomics approaches. Cells were cultured and treated with different concentrations of the ethanolic plant extract. Antitumor activity determined by MTT assay and cell metabolites extracted for NMR spectroscopy. 1H NMR spectroscopy was applied, and outliers were analyzed using multivariate statistical analysis techniques. The extract exhibited antitumor activity against ovarian cancer cells with an IC50 of 6 μg/ml after 48 hours of treatment. The most affected metabolic pathways in the experimental groups were limited to tyrosine metabolism, nucleotide metabolism, fatty acid biosynthesis, and glycerolipid metabolism. The ethanolic root extract of X. Strumarium has antitumor activity on the ovarian cancer cells and can affect vital metabolic pathways of cancer cells.
Ameneh Kargarian
Abstract
The plasma wave acceleration of electron in the bubble regime is investigated in a new configuration containing a planar wiggler. The space-charge field of the laser-created ion channel can focuse and stabilize the electron trajectory to guide it toward the acceleration region. The high-gradient plasma ...
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The plasma wave acceleration of electron in the bubble regime is investigated in a new configuration containing a planar wiggler. The space-charge field of the laser-created ion channel can focuse and stabilize the electron trajectory to guide it toward the acceleration region. The high-gradient plasma wave field can resonantly accelerate the trapped electron to higher energies in the presence of a planar wiggler compensating the electron dephasing. The results show that in the lower plasma wave amplitudes the planar wiggler plays a more significant role on the electron energy enhancement. The increment of the electron energy in this configuration is validated using a three-dimension single-particle code. The electron energy gain dependency on the planar wiggler, ion channel field, plasma wave angle and amplitude as well as the initial energy of electron has been investigated. The results of paper will be of importance in the optimization of electron energy and improving the quality of the accelerated electrons in the plasma wakefield accelerators.
Derick Erl Sumalapao; Leon Elijah C. Bagwan; Angelyn R. Lao
Abstract
Challenges such as advances in technology, demands of global market, and limited warehouse spaces resort manufacturing industries to subcontracting. Subcontracting has been a considerable alternative in the manufacturing industries and is utilized as a strategic tool to diminish operation costs primarily ...
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Challenges such as advances in technology, demands of global market, and limited warehouse spaces resort manufacturing industries to subcontracting. Subcontracting has been a considerable alternative in the manufacturing industries and is utilized as a strategic tool to diminish operation costs primarily to address the problem of scarcity when the firm faces a large demand on the commodity it supplies. The present study employed a mathematical model among firms engaging in subcontracting in search for an optimal schedule in the manufacture of the product and distribution of production time involved with an objective of obtaining a maximum profit. The constraints in the mathematical formulation included the total demand, processing capacity, available supply, processing rate, and time. The plausibility and possible utility of the mathematical model has been explored employing sequential quadratic programming algorithm in the search of the optimal solutions.
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