NH4I-Catalyzed Selective Synthesis of 2-Substituted Benzimidazoles

Veni, P. Rama Krishna; Rani, Usha; Saradhi, Vijaya; Sekhar, D. Chandra

doi:10.22059/jsciences.2026.408328.1007980

NH4I-Catalyzed Selective Synthesis of 2-Substituted Benzimidazoles

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Authors

P. Rama Krishna Veni ¹

Usha Rani ²

Vijaya Saradhi ³

D. Chandra Sekhar ⁴

¹ Department of Applied Sciences &amp;amp;amp;amp;amp;amp;amp;amp; Humanities, Sasi Institute of Technology &amp;amp;amp;amp;amp;amp;amp;amp; Engineering, Tadepalligudem, West Godavari-534101, Andhra Pradesh, India

² Department of Basic Science and Humanities, Vignan’s Lara Institute of Technology and Science, Vadlamudi, Guntur-522213, Andhra Pradesh, India

³ Department of Science and Humanities, KITS Akshar Institute of Technology, Yanamadala, Prathipadu (M), Guntur-522019, Andhra Pradesh, India

⁴ Department of Engineering Chemistry, SRKR Engineering College, Bhimavaram-534204, Andhra Pradesh, India

10.22059/jsciences.2026.408328.1007980

Abstract

By reacting 1,2-diamines with aromatic, aliphatic, and heteroaromatic nitroalkenes while using ammonium iodide (NH4I) as a green catalyst, a simple, effective, and environmentally friendly synthetic pathway was created for the selective synthesis of 2-substituted benzimidazole derivatives in good to excellent yields (78-94%). A plausible reaction mechanism was proposed, and the scope and limitations were further examined.

Keywords

green catalyst

2-substituted benzimidazoles

1,2-diamines

chemoselectivity

Subjects