Some new macrocyclic dibenzotrioxadiamides, dibenzotetraoxadiamide,
dibenzopentaoxadiamide, dibenzothiatrioxadiamide, tribenzotrioxadiamides and
tetrabenzohexaoxadiamide (14-21), (26) and (27) have been prepared. These
compounds were obtained in the macrocyclization step by reacting the diamine (4)
with appropriak dicaxboxylic acid dichlorides (5-13) and (24). The cyclization does
not require high dilution techniques or template effect and provides the expected
dilactams in high yields ranging from 70% to 95%.