SYNTHESIS OF PURINE ACYCLONUCLEOSIDES HAVING PRONOUNCED ANTIVIRAL ACTIVITY

Abstract
The synthesis of a series of purine analogues of the acyclonucleoside
compound 14 (acyclovir) is described. Compounds in this series have been
shown to have pronounced activity against herpes virus-type l(HSV-1).
The anti-viral activities of other analogs whose syntheses were recently
reported [1] by us are also described