Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles
(2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole
(15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3-
pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and antifungal activities of compounds 5, 6, and 7 against a number of microorganisms were determined