2,2'-Disubstitutedamino-4-4'-bis-pyrimidines (3a-m) have been prepared by
linking 2,4-dichloro-6-methyl-5-nitropyrimidine (1) with several diamines and
subsequent reaction with suitable amines. Some of these compounds (3c and 3j)
which were reduced catalitically, on treatment with nitrous acid, urea in
pyridine, and boiling thionyl chloride gave the corresponding bistriazolopyrimidin
(6), bis-purines (7), and bis-isothiazolopyrimidines (8). Two
bis-imidazo[l,2-a] pyrimidines (9 and 10) have also been prepared