Abstract
Condensation and cyclization of 5-hydroxy- 1,2,4- thiadiazol-2-yl hydrazine 1
with pyruvic acid, phenacyl bromide, propargyl bromide and ally1 bromide afforded
compounds 2,5,7 3, 4 ,6 and 8 respectively, Reaction of 1 with epichforohydrine
afforded 4-hydroxy-N-[5-hydroxy- 1 ,3,4-thiadiazoly1] pyrazolidine 9
)