The interaction of sodium n-dodecyl sulphate (SDS) with histones in phosphate
buffer pH 6.4 has been studied spectroscopically and by equilibrium dialysis. The
enthalpies of interaction and the spectroscopic data suggest different structural
stability for histones-SDS interaction. The linear relation between enthaly and
absorbtion was determined by the equation of m= , where m is the
stability coefficient of histones-SDS interaction indicating the relationship of the
structural stability of histones-SDS complexes.