Abstract

The Raman spectrum of cyclosporin-A has been recorded in the solid phase. The
conformation of the molecule has been discussed on the basis of Raman data. It has
been concluded that in agreement with X-ray data, cyclosporin-A molecule has an
antiparallel P- pleated sheet conformation. It may have some reverse P- turn
structure in what has been assigned to a random coil conformation.