PYRAZOLINES AND ISOXAZOLINES (I). SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF P-(1-ACYL-3-METHYL-5-ARYL-4 PYRAZOLINOYL / P-(3-METHYL-5-ARYL-4ISOXAZOLINOYL) ARSANILIC ACID

Abstract
4-(acetoacetamido) arsanilic acid (II), which was then condensed with aryl aldehydes.
The resulting product on reaction with hydrazine hydrate and hydroxyl amine
hydrochloride yielded Pyrazolines (IV) and Isoxazolines (V), respectively. The
antimicrobial activity of compounds against a number of microorganisms was
evaluated. Some of these compounds showed significant antimicrobial activity