Efficient Synthesis of Dihydropyrimidine and Amidoalkyl Naphthol Derivatives Using Zinc Chloride-Based Deep Eutectic Systems as Solvent & Catalyst

Mahdipour, M.; Khabazzadeh, H.; Tavakolinejad Kermani, E.

Efficient Synthesis of Dihydropyrimidine and Amidoalkyl Naphthol Derivatives Using Zinc Chloride-Based Deep Eutectic Systems as Solvent & Catalyst

Document Type : Final File

Authors

M. Mahdipour

H. Khabazzadeh

E. Tavakolinejad Kermani

Department of Chemistry, Faculty of Sciences, Shahid Bahonar University of Kerman 7616914111, Kerman, Islamic Republic of Iran

Abstract

Dihydropyrimidine and amidoalkyl naphthol derivatives have been prepared efficiently in a one-pot synthesis using ZnCl₂/urea and ZnCl₂/acetamide deep eutectic systems as reaction medium and homogeneous catalyst. This method offers some advantages such as simple procedure, inexpensive solvent and catalyst and good yields of the final products in short reaction times. The use of non-toxic and environmentally benign catalyst and solvent system are the main remarkable features of this procedure.

Keywords

Deep eutectic

3, 4-dihydropyrimidine

Amidoalkylnaphthol

Homogeneous catalyst