Document Type : Original Paper

Authors

• Pegah Nouraie ¹
• Shahram Moradi Dehaghi ¹
• Alireza Foroumadi ²

¹ Tehran North Branch, Islamic Azad University

² Tehran University of Medical Sciences

Abstract

In this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid is reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic catalyst in this organic transformation. This work was also accompanied by density functional theory (DFT) studies to justify the formation of final products.

Keywords

• 3-aminocoumarin
• Enaminones
• DFT studies

Main Subjects

• Organic Chemistry