LITHIUM PERCHLORATE MEDIATED AMINATION REACTION OF ALDEHYDES: A NOVEL METHOD FOR SYNTHESIS OF N, N-DIALKYL-p-SILYLATED AMINES*

Abstract
P-Silylated N,N-dialkyl amines (5) were easily synthesized in good to
excellent yield from aldehydes (1), trimethylsilyldialkylamines (2), and
trimethylsilylmethylmagnesium chloride (4) in the presence of 5 M lithium
perchlorate solution in diethyl ether. The reaction Of (2) with aldehyde
proceeded smoothly in the LiCI0 , to give the imimum salt (3). Addition of
trimethylsilylmethylrnagnesium chloride (4) gave the desired product